2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase (TIPARP/PA

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase (TIPARP/PA
GSE167205 · GEO

TL;DR — A 518.4 KB bulk RNA-seq deposit (GSE167205, 1 file(s), liver) in the MASLD / NAFLD / NASH data lake. large (6.4 GB).

0. Summary

Biological premise.

This deposit is included in the MASLD (metabolic dysfunction-associated steatotic liver disease) data lake for the following curated reason: large (6.4 GB). No free-text abstract was exposed by the repository API; the measured file inventory below is authoritative for what the deposit contains.

Every file in this dataset is a bulk RNA-seq readout relevant to MASLD / non-alcoholic fatty liver disease (NAFLD) / non-alcoholic steatohepatitis (NASH), landed from GEO.

Assay and processing.

Modality: bulk RNA-seq (repository subtype: bulk-RNAseq). Tier-1 (must-have) for this modality = raw/normalized gene × sample expression matrix + per-sample design; Tier-2 (recommended) = author DE tables, design/contrasts, gene annotation; Tier-3 (optional / raw) = raw reads (FASTQ/BAM in SRA/ENA), reference build + quantifier version. The Completeness line in each dataset block below states, measured from the landed files, which tiers are present.

Sources.

GSE167205 — GEO deposit (large (6.4 GB)).
PMIDs: none recorded in the index for this deposit.


Disease	MASLD / NAFLD / NASH
Assay / modality	bulk RNA-seq — bulk-RNAseq
Organisms	unspecified
Repository	GEO — NCBI GEO FTP
Accession	GSE167205
Access	Public (open); files mirrored in this dataset's `input/` folder.
Number of studies	1
Number of files	1
Total size	518,382 bytes (≈ 518.4 KB)

1. Datasets — sample sources, protocols, experiment design and metadata

Landed sources at a glance.

Source	Access	Files
GEO	public / OPEN-processed	1

The deposit at a glance.

Accession	Description	Organism	Samples	Scale
GSE167205	large (6.4 GB)	unspecified	n/a	1 files · 518.4 KB

GSE167205 — 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase (TIPARP/PA

GEO record · 1 files · 518.4 KB

Sample source. unspecified material; MASLD/NAFLD/NASH context (large (6.4 GB)).
Samples and retention. Sample count not declared in the repository index; see the per-sample metadata file(s) listed below.
Experiment design. Repository subtype: bulk-RNAseq; disease context MASLD/NAFLD/NASH.
Metadata available. See the annotated file table below; per-sample metadata ships in the ISA-Tab / SDRF / metadata file(s) where present.
Files (annotated).

File What it is
GSE167205_200922-HA_RNA-seq_Count_matrix-simple-NEW.csv.gz Gene × sample count matrix (expression) (24,421 data rows × 17 cols)
How this experiment became a dataset. GSE167205 resolved via the GEO record API → 1 open file(s) fetched into this dataset's input/ folder → sizes verified on disk (518,382 bytes (≈ 518.4 KB)).
Completeness (bulk RNA-seq). Present: expression matrix (Tier-1). Not detected among landed files: per-sample design (Tier-1). (Tiers per the matching modality skill; assessment measured from landed filenames/headers.)

File	What it is
`GSE167205_200922-HA_RNA-seq_Count_matrix-simple-NEW.csv.gz`	Gene × sample count matrix (expression) (24,421 data rows × 17 cols)

2. Analyses this atlas supports

Differential expression. Start from GSE167205_200922-HA_RNA-seq_Count_matrix-simple-NEW.csv.gz (expression matrix) to run DESeq2/edgeR or limma contrasts and MASLD signatures.
Cross-cohort MASLD integration. Combine this deposit (GSE167205) with other liver/MASLD datasets in the lake sharing the same modality for meta-analysis.

Reproduce. All files are in this dataset's input/ folder; the source of record is GSE167205 (https://ftp.ncbi.nlm.nih.gov/geo/series/GSE167nnn/GSE167205/suppl/). Re-fetch with the MASLD crawler (masld_download_pass.py --only GSE167205); sizes are verified on disk and recorded in this dataset's metadata.json.

Citation

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase (TIPARP/PA. GEO accession GSE167205. https://ftp.ncbi.nlm.nih.gov/geo/series/GSE167nnn/GSE167205/suppl/