16S rRNA sequencing OTU matrix dataset for: Chlorogenic acid and Scoparone treatment impro
Zhao Tianyi — 2026-06-15T07:13:36Z · Open Access
figshare.32674950 · Figshare
TL;DR — A 70.6 MB multi-omics / other deposit (figshare.32674950, 1 file(s), liver) in the MASLD / NAFLD / NASH data lake. under-mined portal (Figshare); modality=microbiome.
Biological premise.
The following premise is sourced from the repository record (not fabricated).
This dataset contains the 16S rRNA gene high-throughput sequencing operational taxonomic unit (OTU) matrix generated from cecal fecal samples of Sprague-Dawley rats. The data was collected to investigate the therapeutic advantages of a combination of chlorogenic acid and scoparone in a high-fat emulsion-induced non-alcoholic fatty liver disease (NAFLD) model. Total genomic DNA was extracted, and the V3–V4 hypervariable regions of the bacterial 16S rRNA gene were amplified and sequenced on an Illumina NovaSeq 6000 platform.
Every file in this dataset is a multi-omics / other readout relevant to MASLD / non-alcoholic fatty liver disease (NAFLD) / non-alcoholic steatohepatitis (NASH), landed from Figshare.
Assay and processing.
Modality: multi-omics / other (repository subtype: microbiome). Tier-1 (must-have) for this modality = the rawest deposited measurement table + a sample/condition design table; Tier-2 (recommended) = annotation/feature table, author result tables; Tier-3 (optional / raw) = raw signal + reference + tool versions. The Completeness line in each dataset block below states, measured from the landed files, which tiers are present.
Sources.
| Disease | MASLD / NAFLD / NASH |
| Assay / modality | multi-omics / other — microbiome |
| Organisms | unspecified |
| Repository | Figshare |
| Accession | figshare.32674950 |
| Access | Public (open); files mirrored in this dataset's input/ folder. |
| Number of studies | 1 |
| Number of files | 1 |
| Total size | 70,611,709 bytes (≈ 70.6 MB) |
| License | CC BY 4.0 |
Landed sources at a glance.
| Source | Access | Files |
|---|---|---|
| Figshare | public / OPEN-processed | 1 |
The deposit at a glance.
| Accession | Description | Organism | Samples | Scale |
|---|---|---|---|---|
| figshare.32674950 | under-mined portal (Figshare); modality=microbiome | unspecified | n/a | 1 files · 70.6 MB |
Figshare record · 1 files · 70.6 MB
Sample source. unspecified material; MASLD/NAFLD/NASH context (under-mined portal (Figshare); modality=microbiome).
Samples and retention. Sample count not declared in the repository index; see the per-sample metadata file(s) listed below.
Experiment design. Repository subtype: microbiome; disease context MASLD/NAFLD/NASH.
Metadata available. See the annotated file table below; per-sample metadata ships in the ISA-Tab / SDRF / metadata file(s) where present.
Files (annotated).
| File | What it is |
|---|---|
CD-16s-chen.zip | Compressed archive (ZIP) |
How this experiment became a dataset. figshare.32674950 resolved via the Figshare record API → 1 open file(s) fetched into this dataset's input/ folder → sizes verified on disk (70,611,709 bytes (≈ 70.6 MB)).
Completeness (multi-omics / other). Present: primary data table(s). (Tiers per the matching modality skill; assessment measured from landed filenames/headers.)
CD-16s-chen.zip; combine with the per-sample metadata file to reproduce the deposit's headline numbers.Reproduce. All files are in this dataset's input/ folder; the source of record is figshare.32674950 (https://figshare.com/articles/dataset/_/32674950). Re-fetch with the MASLD crawler (masld_download_pass.py --only figshare.32674950); sizes are verified on disk and recorded in this dataset's metadata.json.
Zhao Tianyi. 16S rRNA sequencing OTU matrix dataset for: Chlorogenic acid and Scoparone treatment impro. Figshare accession figshare.32674950. https://doi.org/10.6084/m9.figshare.32674950.v1